There’s a wave of interest right now in using psychedelic medicines in place of conventional antidepressants, and for good reason. The research coming out over the past few years has been remarkable.
But there’s a problem hiding inside that enthusiasm, and almost nobody in our field is talking about it.
Most psychedelic medicines don’t combine safely with serotonergic antidepressants. Put them together and you introduce the risk of serotonin syndrome, a medical emergency serious enough that Dr. Rabin has built his teaching around one blunt sentence: the worst place a psychedelic experience can land you is in the ER.
In this clip, Dr. Rabin explains why this matters for you specifically, whether you’re a coach, a licensed clinician, or a facilitator.
Millions of adults in this country take a serotonergic antidepressant.
They are the people filling your inbox with questions about psychedelic work. If you practice in this field for any length of time, you will sit across from a client who is on one of these medications and wants to know what comes next.
Dr. Rabin is a board-certified psychiatrist and neuroscientist, one of the few in the country trained in advanced psychedelic-assisted therapy who also carries a general psychiatric caseload.
His answer to this problem isn’t “turn those clients away.” It’s a protocol, one he uses in his own practice and now teaches to practitioners.
Press play. It’s one minute, and it reframes the next two years of your practice.
SSRI Deprescribing & Psychedelic Readiness Certification

Learn the full protocol directly from Dr. Dave Rabin. Six live 90-minute sessions, six facilitated labs where you work real cases, and pre-publication access to his clinical deprescribing manual. Three months, starting October 7. 7.5 CE credits available for eligible clinicians.
SEE THE FULL CURRICULUM →
Next in this series: Most people who start one of these medications are never given a plan for coming off. Dr. Rabin explains why that happened, and what indigenous ceremony traditions and Western clinical protocols already agree on.